Chang Hoon Ji
Executive Director AUTOTAC Bio
I am a molecular and cellular biologist by training, working at the Cellular Degradation Biology Center in Seoul National University as a Research Associate Professor on the basic/translational science on autophagic Arg/N-degron pathway, as well as at AutotacBio, Inc. as the Chief Technology Officer on the drug development of heterobifunctional chimeric targeted protein degraders. My personal goal is to cover the entire width of the ‘basic science – translational science – clinical development’ spectrum for a comprehensive understanding and advancement of human health.
Seminars
Wednesday 9th December 2026
Introducing the First Multimodal TPD Platform: Degrading Tau Aggregates & Restoring CNS Autophagy in AD, PSP & Canine Dementia
11:30 am
- Demonstrating how AB-12 and AB-19 target intracellular tau neurofibrillary tangles while restoring cognitive, behavioural and neuromuscular functions
- Elucidating the mechanisms underpinning the AUTOTAC platform’s ability to reactivate dysfunctional levels of CNS autophagy
- Showcasing phase I data from AB-12 and phase II results from the AB-81 study in canine dementia
