Jae-young Koh
Chief Scientific Officer Zincure
Prof. Jae-young Koh serves as Chief Science Officer and Professor of Neurology at Asan Medical Center, University of Ulsan College of Medicine. A Stanford University PhD graduate and former Director of the Asan Life Science Institute, Prof. Koh is an internationally recognised neuroscience researcher with 178 SCI publications, more than 31,000 citations, and an h-index of 75. His distinguished career has been recognised with numerous honours, including the Frederickson Prize from the International Society for Zinc Biology and the Korean Ministry of Health Technology Contribution Commendation.
Seminars
Wednesday 9th December 2026
Restoring Lysosomal Function to Enable TDP‑43 Clearance: ZCS1 as a Disease-Modifying Strategy in ALS
4:30 pm
- Deciphering how ZCS1 promotes reactivation of lysosome enzymatic function via TFEB regulation
- Demonstrating TDP-43 clearance and NfL reduction in (SOD1)-G93A mouse models
- Future directions for progressing towards GLP toxicology studies and first-in-human trials in 2027
